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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D23
All Species:
40.61
Human Site:
Y658
Identified Species:
81.21
UniProt:
Q9NUY8
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NUY8
NP_060779.2
699
78322
Y658
P
E
L
I
T
F
K
Y
G
N
S
S
A
S
G
Chimpanzee
Pan troglodytes
XP_001142898
699
78360
Y658
P
E
L
I
T
F
K
Y
G
N
S
S
A
S
G
Rhesus Macaque
Macaca mulatta
XP_001089575
699
78401
Y658
P
E
L
I
T
F
K
Y
G
N
S
S
A
S
G
Dog
Lupus familis
XP_535717
699
78459
Y658
P
E
L
I
T
F
K
Y
G
N
S
N
A
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0F1
684
76407
Y643
P
E
L
I
T
F
K
Y
G
N
S
S
A
S
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518998
1159
128900
Y1118
P
E
L
I
T
F
K
Y
G
N
S
S
A
A
G
Chicken
Gallus gallus
Q5F415
679
75993
Y638
P
E
L
I
T
F
K
Y
G
N
S
N
T
S
G
Frog
Xenopus laevis
Q6NRC7
682
76832
Y641
P
E
L
I
T
F
K
Y
G
S
S
N
A
S
G
Zebra Danio
Brachydanio rerio
Q7SXV1
680
76081
F638
P
E
L
I
T
F
K
F
G
N
N
N
A
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608569
689
77454
Y649
R
D
L
I
T
F
K
Y
G
F
P
D
G
D
G
Honey Bee
Apis mellifera
XP_624741
648
73025
Y608
S
D
L
I
T
F
K
Y
G
T
T
Q
Y
N
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788039
808
91017
Y684
S
E
F
I
T
F
R
Y
G
R
V
N
A
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.1
96.4
N.A.
92.1
N.A.
N.A.
54.6
87.1
80.2
75.2
N.A.
44.9
41.3
N.A.
38.3
Protein Similarity:
100
99.4
99.1
98
N.A.
95.8
N.A.
N.A.
56.9
92.5
88.2
84.8
N.A.
61.7
59.7
N.A.
55
P-Site Identity:
100
100
100
93.3
N.A.
100
N.A.
N.A.
93.3
86.6
86.6
73.3
N.A.
53.3
46.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
93.3
100
100
N.A.
60
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
75
25
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
17
0
0
0
0
0
0
0
0
0
9
0
9
9
% D
% Glu:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
100
0
9
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
9
0
92
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
92
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
92
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
67
9
42
0
9
0
% N
% Pro:
75
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% Q
% Arg:
9
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% R
% Ser:
17
0
0
0
0
0
0
0
0
9
67
42
0
59
0
% S
% Thr:
0
0
0
0
100
0
0
0
0
9
9
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _